Abstract Induced oncoproteins degradation provides an attractive anti-cancer modality. Activation of anaphase-promoting complex (APC/CCDH1) prevents cell-cycle entry by targeting crucial mitotic proteins for degradation. Phosphorylation of its co-activator CDH1 modulates the E3 ligase activity. but little is known about its regulation after phosphorylation and how to effectively harne... https://leoners.shop/product-category/dining-chair-cushion/