Epidemiological studies suggest cigarette smoking as a probable environmental factor for a variety of congenital anomalies. including low bone mass. increased fracture risk and poor skeletal health. Human and animal in vitro models have confirmed hypomineralization of differentiating cell lines with sidestream smoke being more harmful to developing cells than mainstream smoke. https://www.roneverhart.com/L-Homme-Ideal-Cologne-by-Guerlain/